The DVORAK Keyboard Layout is an alternate way to layout the keys on a keyboard created back in 1936 by Dr. Dvorak. They keys are laid out so less finger motion is needed. The common QWERTY layout was chosen to prevent typewriters from getting stuck.
It has a potential to help Carpal Tunnel Syndrome or wrist pain because of this more optimal layout. Common letter combinations require less motion and less awkward finger movement. Letters are alternately typed by hands and the most common letters are easier to type. This is not a slamdunk, because the weaker small fingers are used more often in the DVORAK layout. Some argue that switching keyboard layouts just changes the burden onto other fingers, resulting only in short term gains.
Some ergonomic keyboards like the pictured Kinesis have DVORAK keycaps available. Wrist Pain – Carpal Tunnel Syndrome takes time to heal, so go easy on the computer.