One of the first steps people take when diagnosed with a RSI such as carpal tunnel syndrome, is to switch to an ergonomic keyboard. Here are some ergonomic keyboard that I have and continue to use and recommend.
The DVORAK Keyboard Layout is an alternate way to layout the keys on a keyboard created back in 1936 by Dr. Dvorak. They keys are laid out so less finger motion is needed. The common QWERTY layout was chosen to prevent typewriters from getting stuck.